Scientific Programme


* Scientific Program subject to change

Monday, 27 May 2019

07:45-17:20

Registration 

08:40-08:45

Welcome and Opening of the Congress
David Tanne, Rambam Health Care Campus, Israel

08:45-10:15

Neuroscience Innovation
Chairpersons: Michael Chopp, Henry Ford Health System, USA
Paul Fishman, University of Maryland School of Medicine, USA

08:45-09:10

Brain Proteomics: From Basic Research to Diagnostic Application
Jean-Charles Sanchez, University of Geneva, Switzerland

09:10-09:35

Exosome Therapy for Stroke and Neural Injury
Michael Chopp, Henry Ford Health System, USA

  • Exosomes, biological bilipid layer nanoparticles, mediate intercellular communication.  They contain microRNAs which can concurrently regulate posttranscriptional translation of hundreds of genes
  • Exosomes from select cell populations can be effectively used to treat neurological diseases and injury
  • The microRNA content of exosomes can be engineered to optimize and to target therapeutic interventions

09:35-10:00

Beyond Immunointervention: Repair as Treatment Target in MS
Hans-Peter Hartung, Heinrich-Heine-University Düsseldorf, Germany

10:00-10:15

Panel Discussion & Q&A

10:15-10:45

Networking, Coffee Break and visit the Exhibition 

10:45-12:15

Migraine Innovation & Technology
Chairpersons: David Yarnitsky, Rambam Health Care Campus, Israel
Cicek Wöber-Bingöl, Medical University of Vienna, Austria

10:45-11:10

Drugs in Treatment of Migraine
Manjit Matharu, University College London Hospitals NHS Foundation Trust, UK

  • 5HT-1F receptor agonists (ditans)
  • Calcitonin Gene Related peptide (CGRP) receptor antagonists (gepants)
  • Calcitonin Gene Related peptide (CGRP) receptor and ligand monoclonal antibodies

11:10-11:35

Brain Excitability in Migraine
Marina de Tommaso, Bari Aldo Moro University, Italy

  • Main characteristics of migraine
  • The concept of migraine as an “oscillopathy”
  • Possible basis of CSD generation

11:35-12:00

Devices in Treatment of Migraine
David Yarnitsky, Rambam Health Care Campus, Israel

12:00-12:15

Panel Discussion & Q&A

12:15-13:00

Networking, Lunch Break and visit the Exhibition 

13:00-14:30

Neuro-Stimulation & Neuromodulation
Chairpersons: François Alesch, Medical University of Vienna, Austria
Walter Paulus, University Medical Center Göttingen, Georg August University, Germany

13:00-13:25

Focused Ultrasound: An Emerging Therapeutic Modality for Neurologic Disease
Paul Fishman, University of Maryland School of Medicine, USA

  • MRI guided HIFU for minimally invasive targeted brain ablation
  • Opening the Blood-Brain Barrier with FUS
  • Neuromodulation with low intensity FUS

13:25-13:50

SphenoPalatine Ganglion Stimulation for Acute Stroke and Beyond
Natan M. Bornstein, Shaare Zedek Medical Center, Israel

13:50-14:15

Transcranial Brain Stimulation
Walter Paulus, University Medical Center Göttingen, Georg August University, Germany

  • Transcranial magnetic stimulation
  • Transcranial electric stimulation
  • Human neuroplasticity

14:15-14:30

Panel Discussion & Q&A

14:30-15:00

Networking, Coffee Break and visit the Exhibition

15:00-16:20

BrainHIT Start Up Innovation Fair
Chairpersons: Sagi Harnof, Rabin Medical Center, Israel
David Tanne, Rambam Health Care Campus, Israel

15:00-15:10
TBIcheckTM: A Portable Device to Detect Mild Traumatic Brain Injury Measuring Brain Biomarkers from A Finger Prick
Alberto Schena
, Jean-Charles Sanchez, Sébastien Iva, ABCDx SA, Switzerland 

15:10-15:20
Celloscope - a smartphone app to monitor stroke and acute neurological disorders using common smartphone sensors
Tomer Shussman
, Celloscope Ltd., Israel
 
15:20-15:30
PREDICT – Personalizing Depression Treatment
Charlotte Baumeister
, Elminda, Israel

15:30-15:40
Granagard: A "Smart" Food Supplement, Targets Natural Lipid Antioxidants to the Brain for the Prevention of Neurodegenerative Diseases
Ruth Gabizon, Orli Binyamin, Kati Frid, Granalix Biotechnologies, Israel

15:40-15:50  
Early In-Vitro Diagnostic Test on Perinatal Asphyxia and Hypoxic Ischemic Encephalopathy in Newborns
Ron Meyer
, InfanDx AG, Germany

15:50-16:00  
A New Approach for Patients Suffering from Epilepsy – The EASEE®-Transcranial Neuro-Stimulation System
Erdmann J. Zippel
, Precisis AG, Germany

16:00-16:10  
A Novel Therapy for Treatment of Neurological Disorders
Jordan Rubinson, Zadik Hazan, Yoni Weiss, Konstantin Adamsky, Regenera Pharma, Israel

16:10-16:20  
TBIFinder inc.: A Data Analytics Company that Provides Objective Concussion Diagnosis to Improve Personal Injury Claim Outcomes
Nicholas Simard
, Michael D. Noseworthy, Dinesh Kumbhare, TBIFinder inc., Canada


16:20-17:00

Oral Presentations
Chairperson: David Tanne, Rambam Health Care Campus, Israel
16:20-16:28
Personalizing Digital Health to Improve the Treatment Outcomes and Quality of Life in Patients with Complex Brain Disorders
Paramala Santosh
, Jatinder Singh, Nantia Iakovidou, Federico Fiori, UK

16:28-16:36

Cellphone Application as Innovation for Treatment Management of Acute Stroke
Dmitry Rozenfeld
, Anna Reznik, Yael Safran, Prometheus Computer Team, Israel

16:36-16:44

Brain Health Coaching App (BHCA)
Javier Solana-Sanchez
, David Bartres-Faz, Gabriele Cattaneo, Catherine Pachon-Garcia, Didac Macia-Bros, Timothy Morris, Jose Maria Tormos-Muñoz, Alvaro Pascual-Leone, Spain

16:44-16:52

Cardiovascular Reactivity
Patrizia Fiori, Antonio Corbo, Giulia Corbo, Luigi Iorillo, Guglielmo Capaldo, Chiara Pelosi, Patrizia Savino, Gennaro Bellizzi, Filomena Botticella, Carmela Dragonetti, Alessandro Morella, Vincenzo Pellecchia, Giuseppina Romano, Erminio Pace, Sergio Landi, Marianna Raffa, Emerico Mazza, Carminantonio Tammaro, Luigi Maria Giannetti, Antonio Monaco, Italy

16:52-17:00

CSF Exchange Therapy, Using Artificial CSF Enriched with Mesenchymal Stem Cells Secretions, For the Treatment of Inflammatory/Degenerative Diseases of the CNS 
Michael Valitsky, Sandrine Benhamron, Keren Nitzan, Ezra Ella, Dimitrios Karussis, Oded Abramsky, Ibrahim Kassis, Hanna Rosenmann, Israel


17:00-17:08


Misfolded Proteins in the Retina
Umur Kayabasi
, Turkey


Tuesday, 28 May 2019

08:30-16:30

Registration

09:00-10:30

Behavior & Cognition
Chairpersons: Masud Husain, University of Oxford, UK
Frank-Erik de Leeuw, Radboud University Nijmegen Medical Center, The Netherlands

09:00-09:25

Brain Mechanisms Underlying Motivation and Apathy in Health and Disease
Masud Husain, University of Oxford, UK

  • Apathy is a syndrome associated with profound lack of motivation to initiate actions which is frequently observed across many neurological diseases
  • Recent evidence from animal and human studies has led to a common, transdiagnostic framework to understand apathy
  • One common mechanism across diseases may be blunting of sensitivity to reward

09:25-09:50

ADappt – An Online Tool to Support the Diagnosis of Mild Cognitive Impairment and Alzheimer’s Disease
Ingrid van Maurik, Amsterdam UMC, The Netherlands

  • ADappt is an online tool, developed in co-creation, to support clinicians in the diagnostic process
  • ADappt facilitates the interpretation and communication of biomarker results and supports clinicians to engage patients in diagnostic decision making
  • ADappt was considered valuable by clinicians, patients and caregivers

09:50-10:15

The Orchestra of the Phytocannabinoids in the Brain
Gil Lewitus, 
Technion, Israel Institute of Technology, Israel

10:15-10:30

Panel Discussion & Q&A

10:30-11:00

Networking, Coffee Break and visit the Exhibition 

11:00-12:30

Advancing Science and Technologies for NeuroWellness
Chairpersons: Gilad Peleg, Joy Ventures, Israel
Hans-Peter Hartung, Heinrich-Heine-University Düsseldorf, Germany

11:00-11:15

Spotlight on NeuroWellness
Gilad Peleg
Co-Founder & Chairman, Joy Ventures, Israel

11:15-11:45

New Directions in Emotion Regulation Research
Michael Gilead
Symbolic Cognition and Interaction (SCI) Lab, Israel

11:45-12:15

Guided EEG-Based Training for Cognitive Wellness
Aziz Kaddan
Myndlift, Israel

12:15-12:30

Panel Discussion & Q&A

12:30-13:30

Networking, Lunch Break and visit the Exhibition

13:30-15:00

Cerebrovascular Disease/Stroke I
Chairpersons: Wilfried Lang, Barmherzige Brüder, Krankenhaus Wien, Austria
David Tanne, Rambam Health Care Campus, Israel

13:30-13:55

Cerebral Small Vessel Disease: From A Focal to A Global Perspective
Frank-Erik de Leeuw, Radboud University Nijmegen Medical Center, The Netherlands

13:55-14:20

Stroke-Emergency-Mobile (STEMO) with Integrated CT-Scanner and Point-Of-Care Laboratory
Heinrich Audebert, Charité, Germany

  • Time is brain rationale in stroke
  • The concept of prehospital stroke treatment in mobile stroke units
  • Effects of the implementation of STEMO on time to treatment and outcome

14:20-14:45

Promising Novel Devices and Technology for Acute Stroke Treatment
Marc Ribo, Hospital Vall d’Hebron, Spain

  • Faster selection of adequate candidates
  • Improved devices
  • Adjunctive therapies

14:45-15:00

Panel Discussion & Q&A

15:00-15:30

Networking, Coffee Break and visit the Exhibition 

15:30-16:30
Cerebrovascular Disease/Stroke II
Chairpersons: Marc Ribo, Hospital Vall d’Hebron, Spain
Heinrich Audebert, Charité, Germany

15:30-15:55
Stroke Economix for Patient Access: A NEW Approach
Matthieu Cuche,
Medtronic, Switzerland

15:55-16:20  
Improving the Stroke Workflow Using Real Time Location Tracking and The Co-Design of The Stroke Communication Tool
Evert van Loenen,
Philips, The Netherlands
  • Co-designing process with a hospital partner
  • The design of a stroke communication tool
  • Using real-time location tracking for quantitatively measuring the effect of a solution
16:20-16:30
Panel Discussion & Q&A

16:30-16:40

Closing remarks
David Tanne, Rambam Health Care Campus, Israel